Implicación de la Corteza Insular en la evocación de las preferencias gustativas condicionadas
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2022-04-05
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El papel de la corteza insular (CI) ha sido muy estudiado en relación con la memoria y el aprendizaje. La administración de lidocaína inactivó la CI tras la adquisición del aprendizaje apetitivo gustativo (AApG) inducido por glucosa, que consistió en 5 ensayos en los cuales tanto al grupo control como al grupo experimental se les presentaban dos buretas simultáneamente con dos sabores: fresa (F) y coco (C). La ingesta de uno de los sabores se emparejó con la administración de glucosa y el otro sabor con suero fisiológico (SF). Posteriormente, se inactivó la CI (Día 6) y fueron sometidos a la prueba de discriminación, el grupo experimental no mostró AApG mientras que el grupo control sí. Una vez revertida la acción de la lidocaína (Día 7), ambos grupos mostraron aprendizaje. En virtud de ello, estos resultados sugieren que la inactivación de la CI bloquea las preferencias gustativas condicionadas.
The role of the insular crust (IC) has been extensively studied in relation to memory and learning. The administration of lidocaine inactivated IC after the acquisition of the Taste Appetitive Learning (TAL) induced by glucose, which consisted of 5 trials in which both the control group and the experimental group were presented with two burettes simultaneously with two flavors: strawberry (S) and coconut (C). The intake of one of the flavors was paired with the administration of glucose and the other flavor with physiological saline (PS). Subsequently, the IC was inactivated (Day 6) and they were subjected to the discrimination test, the experimental group did not show TAL while the control group did. Once the action of lidocaine was reversed (day 7), both groups showed learning. By virtue of this, these results suggest that IC inactivation blocks conditioned preferences.
The role of the insular crust (IC) has been extensively studied in relation to memory and learning. The administration of lidocaine inactivated IC after the acquisition of the Taste Appetitive Learning (TAL) induced by glucose, which consisted of 5 trials in which both the control group and the experimental group were presented with two burettes simultaneously with two flavors: strawberry (S) and coconut (C). The intake of one of the flavors was paired with the administration of glucose and the other flavor with physiological saline (PS). Subsequently, the IC was inactivated (Day 6) and they were subjected to the discrimination test, the experimental group did not show TAL while the control group did. Once the action of lidocaine was reversed (day 7), both groups showed learning. By virtue of this, these results suggest that IC inactivation blocks conditioned preferences.
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Psicología aplicada a los ámbitos clínico y de la salud Intervención Psicosocial