Eficacia del ácido acético para el tratamiento de heridas infectadas por pseudomona aeuroginosa
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2024-05-08
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El ácido acético es un producto que lleva usándose siglos en la medicina, sin embargo, actualmente en nuestro entorno, carece de uso en este ámbito. A pesar de ello, se ha estudiado su utilidad frente a un tipo de bacteria concreto: Pseudomona aeuroginosa. Se trata de una especie Gram negativa que en los últimos años está adquiriendo resistencia a un número cada vez más elevado de antibióticos, dificultando así su erradicación y generando elevadas tasas de morbimortalidad. Por ello nuestro estudio se centra en tres objetivos principalmente: conocer los efectos que provoca el ácido acético en Pseudomona aeuroginosa; las posibles diferencias entre antisépticos usados comúnmente para curas y el ácido acético; y por último conocer las concentraciones de vinagre necesarias para eliminar Pseudomona aeuroginosa y/o permita la cicatrización de heridas. Para llevar a cabo la búsqueda, se consultaron las siguientes bases de datos internacionales de ciencias de la salud: Cochrane, Cinhal, Lilacs, Web Of Science, Medline y PubMed. Se utilizaron distintas cadenas de búsqueda para cada una de las bases mencionadas. Entre todos los resultados obtenidos, tras aplicar los criterios de inclusión y exclusión, se seleccionaron 24 para la realización del presente estudio. Los tipos de estudios que se incluyeron fueron revisiones de la literatura, estudios in vitro, estudio de casos, ensayos clínicos entre otros. La búsqueda se llevó a cabo entre noviembre de 2022 y enero de 2023. Los resultados que se obtuvieron de los estudios in vitro es que Pseudomona aeuroginosa se inhibía/erradicaba con ácido acético a concentraciones entre 0,16% y 5%. En los casos con heridas, se mostró que concentraciones máximas de 5% de ácido acético, eliminaban rápidamente la bacteria y no interferían en el proceso de cicatrización. Aunque los resultados parecen prometedores, se hace necesaria mayor investigación, pues el ácido acético como antiséptico podría suponer grandes ventajas en el sistema sanitario
Acetic acid is a product that has been used for centuries in medicine, however, currently in our environment, it lacks use in this field. However, its usefulness has been studied against a specific type of bacteria: Pseudomona aeuroginosa. This is a Gram-negative species that in recent years is acquiring resistance to an increasing number of antibiotics, thus making its eradication difficult and generating high morbidity and mortality rates. Therefore, our study focuses on three main objectives: to know the effects of acetic acid on Pseudomona aeuroginosa; the possible differences between commonly used antiseptics for cures and acetic acid; and finally, to know the concentrations of vinegar necessary to eliminate Pseudomona aeuroginosa and/or to allow wound healing. To carry out the search, the following international health sciences databases were consulted: Cochrane, Cinhal, Lilacs, Web Of Science, Medline and PubMed. Different search strings were used for each of the aforementioned databases. Among all the results obtained, after applying the inclusion and exclusion criteria, 24 were selected for the present study. The types of studies included were literature reviews, in vitro studies, case studies, clinical trials, among others. The search was conducted between November 2022 and January 2023. The results obtained from the in vitro studies is that Pseudomona aeuroginosa was inhibited/eradicated by acetic acid at concentrations between 0.16% and 5%. In cases with wounds, it was shown that maximum concentrations of 5% acetic acid rapidly eliminated the bacteria and did not interfere with the healing process. Although the results seem promising, further research is needed, as acetic acid as an antiseptic could have great advantages in the health care system.
Acetic acid is a product that has been used for centuries in medicine, however, currently in our environment, it lacks use in this field. However, its usefulness has been studied against a specific type of bacteria: Pseudomona aeuroginosa. This is a Gram-negative species that in recent years is acquiring resistance to an increasing number of antibiotics, thus making its eradication difficult and generating high morbidity and mortality rates. Therefore, our study focuses on three main objectives: to know the effects of acetic acid on Pseudomona aeuroginosa; the possible differences between commonly used antiseptics for cures and acetic acid; and finally, to know the concentrations of vinegar necessary to eliminate Pseudomona aeuroginosa and/or to allow wound healing. To carry out the search, the following international health sciences databases were consulted: Cochrane, Cinhal, Lilacs, Web Of Science, Medline and PubMed. Different search strings were used for each of the aforementioned databases. Among all the results obtained, after applying the inclusion and exclusion criteria, 24 were selected for the present study. The types of studies included were literature reviews, in vitro studies, case studies, clinical trials, among others. The search was conducted between November 2022 and January 2023. The results obtained from the in vitro studies is that Pseudomona aeuroginosa was inhibited/eradicated by acetic acid at concentrations between 0.16% and 5%. In cases with wounds, it was shown that maximum concentrations of 5% acetic acid rapidly eliminated the bacteria and did not interfere with the healing process. Although the results seem promising, further research is needed, as acetic acid as an antiseptic could have great advantages in the health care system.